Diabetes Risk After Treatment for Childhood and Young Adult Cancer
Cromie KJ. Murray RD. Ajjan RA, Hughes NF, Feltbower RG, Glaser AW. Diabetes Risk After Treatment for Childhood and Young Adult Cancer. Diabetes Care. 2025 Jan 24:dc242171. doi: 10.2337/dc24-2171. Online ahead of print. doi.org/10.2337/dc24-2171
Survival Outcomes Following Chemotherapy for High-Grade Central Nervous System Tumors in Adolescents and Young Adults: An Exploration of Variations According to Ethnicity and Deprivation
Introduction: Adolescents and young adults (AYA) are a unique subgroup of patients who experience cancer at the interface between pediatric and adult oncology services. Central nervous system (CNS) tumors are the leading cause of cancer-related morbidity and mortality in this group. Socioeconomic status and ethnicity are known to impact CNS tumor survival in patients of […]
From Storage to Survivorship: A Scoping Review of Young Adult Cancer Survivors’ Experiences and Preferences in Reproductive Survivorship Care After Fertility Tissue Preservation
Despite improved survival rates for childhood cancer, around 60% of survivors suffer lifelong health problems due to their treatment, including fertility issues which account for one third of these problems. Ovarian or testicular tissue cryopreservation can be offered to patients whose cancer treatment puts them at high risk of subsequent subfertility, but it presents unique […]
Protocol for the ‘Supporting Young Cancer Survivors who Smoke’ study (PRISM): Informing the development of a smoking cessation intervention for childhood, adolescent and young adult cancer survivors in England
BACKGROUND: Childhood, adolescent and young adult (CAYA) cancer survivors are vulnerable to adverse late-effects. For CAYA cancer survivors, tobacco smoking is the most important preventable cause of ill-health and early death. Yet, effective strategies to support smoking cessation in this group are lacking. The PRISM study aims to undertake multi-method formative research to explore the […]
Early educational attainment in children with major congenital anomaly in the UK
CONCLUSIONS: These novel results demonstrate that poor educational attainment extends to children with urinary, limb and gastrointestinal CAs. We demonstrate the need for collaboration between health and education services to assess and support children with major CA, so every CA survivor can maximise their potential. Arch Dis Child. 2024 Mar 19;109(4):326-333. doi: 10.1136/archdischild-2023-326471. ABSTRACT OBJECTIVE: […]
Health-related quality of life after a diagnosis of bladder cancer: a longitudinal survey over the first year
OBJECTIVES: To describe the health-related quality of life (HRQoL) of patients in a prospective 12-month observational cohort study of new bladder cancer diagnoses and compare with national cancer and general population surveys. BJU Int. 2024 Apr;133(4):460-473. doi: 10.1111/bju.16242. Epub 2023 Dec 13. ABSTRACT OBJECTIVES: To describe the health-related quality of life (HRQoL) of patients in […]
Educational attainment of children with congenital heart disease in the United Kingdom
CONCLUSION: Children with CHD have lower educational attainment compared with their peers. Deficits are evident from school entry and increase throughout primary school. Eur Heart J Qual Care Clin Outcomes. 2024 Aug 8;10(5):456-466. doi: 10.1093/ehjqcco/qcad068. ABSTRACT BACKGROUND: Educational attainment in children with congenital heart disease (CHD) within the UK has not been reported, despite the […]
Evaluation of cardiovascular risk factors in long-term survivors of adult- and childhood-onset brain tumours: a pilot study
CONCLUSION: The phenotype of both CO and AO brain tumour survivors is characterized by an adverse metabolic profile and body composition, putatively placing long-term survivors at increased risk of vascular morbidity and mortality. Endocr Connect. 2023 Jul 12;12(8):e220491. doi: 10.1530/EC-22-0491. ABSTRACT BACKGROUND: Survivors of childhood brain tumours (SCBT) and teenage and young adult cancer survivors […]
Identifying the important social outcomes for childhood cancer survivors: an e-Delphi study protocol
INTRODUCTION: Optimising the health of childhood cancer survivors is important given the high long-term survival rate coupled with a significant late effects burden. Included within the WHO’s definition of ‘Health’ are social outcomes. These are of interest given their impact on adult functioning within society, complex interactions with physical and mental health outcomes and potential […]