Does Joint Care Impact Teenage and Young Adult’s Patient-Reported Outcomes After a Cancer Diagnosis? Results from BRIGHTLIGHT_2021

CONCLUSIONS: No evidence that patient-reported outcomes differ by categories of care existed. This may suggest the evolution of TYA cancer services has led to similar outcomes regardless of care category. However, given the small sample size it is not possible to draw firm conclusions.  Cancers (Basel). 2025 Dec 2;17(23):3868. doi: 10.3390/cancers17233868. ABSTRACT BACKGROUND: Healthcare policy […]

Exploring the Coordination of Cancer Care for Teenagers and Young Adults in England and Wales: BRIGHTLIGHT_2021 Rapid Qualitative Study

CONCLUSIONS: Coordination of care is mostly developing; however, the shared vision and goals dimension did achieve full active collaboration. The implementation of a service specification will address regional leadership requirements, but resources are required to extend the delivery of interventions to support coordination and collaboration, allowing the commissioned model of care to be delivered safely.  […]

Educational outcomes for children and young people with cancer: study protocol for a population-based cohort study using linked education and hospital data from England

INTRODUCTION: Childhood cancer survivors (CCSs) experience educational disruptions during and following treatment, yet robust, longitudinal evidence on educational performance remains limited. We will investigate differences in educational outcomes between CCSs and non-cancer peers during primary and secondary school. We will also explore how sociodemographic factors and age at diagnosis contribute to potential differences in General […]

Understanding the needs and experiences of young cancer patients, caregivers and healthcare professionals in the UK following childhood fertility tissue preservation (FTP): a qualitative study informed by patient and public involvement and engagement

CONCLUSIONS: PPIE provided valuable insights into the experiences of childhood cancer survivors with preserved fertility tissue, their parents and clinicians, highlighting priority areas to guide future research and ensure it addresses the concerns of care recipients. Our findings suggest that childhood cancer survivors who preserve tissue for future fertility need personalised follow-up care with information […]

Contribution of ethnicity and deprivation to paediatric critical care outcomes in the UK, 2008-21: a national retrospective cohort study

BACKGROUND: Evidence from UK paediatric intensive care units (PICUs) demonstrates increased incidence of admission among children of Asian and Black ethnicity and children residing in more deprived areas. We aimed to investigate whether mortality in PICU is associated with ethnicity and child poverty.  Lancet Child Adolesc Health. 2025 Sep;9(9):646-654. doi: 10.1016/S2352-4642(25)00156-7. Epub 2025 Jul 10. […]

High-flow nasal cannula therapy versus continuous positive airway pressure for non-invasive respiratory support in paediatric critical care: the FIRST-ABC RCTs

CONCLUSIONS: Among acutely ill children requiring non-invasive respiratory support, high-flow nasal cannula met the criterion for non-inferiority compared with continuous positive airway pressure for time to liberation from respiratory support whereas in critically ill children requiring non-invasive respiratory support following extubation, the non-inferiority of high-flow nasal cannula could not be demonstrated.  Health Technol Assess. 2025 […]